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The methodology seems to be working on our data with our recording systems, but we want to gather more evidence to claim that it is universal and can extend current battery of tests used for examination of motor speech disorders. Therefore, we will ask you to fill the registration form and questionaires to know who use the software and how he or she is satisfied by its performance. The data will be used for improvement of the methodology and presented as an evidence of usefullness / applicability of this tool. The use of the information and software provided is restricted by the following license and without any responsibility on behalf of the creators as mentioned in the disclaimer.

LICENSE: This methodology was designed and tested following high scientific rigor; however, we require to gather more evidence to call it other than experimental. Therefore, the methodology can be used only for non-profit research purposes including experimental use in a clinnical setting. It is prohibited to copy or redistribute the software without the express to subjects not mentioned in the registration forms and questionaires. The methodology can be used only as a whole and can not be incorporated partly or as a whole into any other methodology or software. Each user commits to provide sufficient feedback about this methodology via questionaires or other communication channels if required.

DISCLAIMER: THIS SOFTWARE IS PROVIDED "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL WE BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

The methodology is a product of multidisciplinary research

The research was supported by institutions and grant agencies

The research was published in numerous peer-reviewed papers

J. Rusz, M. Vaneckova, B. Benova, T. Tykalova, M. Novotny, H. Ruzickova, T. Uher, M. Andelova, K. Novotna, L. Friedova, J. Motyl, K. Kucerova, J. Krasensky, D. Horakova. (2019). "Brain volumetric correlates of dysarthria in multiple sclerosis," Brain and Language, 194(7 July): 58-64.

L. Friedova, J. Rusz, J. Motyl, B. Srpova, K. Vodehnalova, M. Andelova, K. Novotna, M. Novotny, H. Ruzickova, T. Tykalova, E. Kubala Havrdova, D. Horakova, and T. Uher. (2019). "Slowed articulation rate is associated with information processing speed decline in multiple sclerosis: A pilot study," Journal of Clinical Neuroscience, 65(7 July): 28-33.

J. Rusz, T. Tykalova, G. Salerno, S. Bancone, J. Scarpelli, M. T. Pellecchia. (2019). "Distinctive speech signature in cerebellar and parkinsonian subtypes of multiple system atrophy," Journal of Neurology, 266(6 June): 1394-1404.

J. Rusz, A. Fecikova, T. Tykalova, R. Jech. (2019). "Effect of pallidal deep-brain stimulation on articulation rate in dystonia," Neurological Sciences, 40(April): 869–873.

J. Rusz, J. Hlavnicka, T. Tykalova, M. Novotny, P. Dusek, K. Sonka, and E. Ruzicka. (2018). "Smartphone allows capture of speech abnormalities associated with high risk of developing Parkinson’s disease," IEEE Transactions on Neural Systems and Rehabilitation Engineering, 26(8 August): 1495-1507.

J. Rusz, T. Tykalova, A. Fecikova, D. Stastna, D. Urgosik, R. Jech. (2018). "Dualistic effect of pallidal deep brain stimulation on motor speech disorders in dystonia," Brain Stimulation, 11(4 July-August): 896-903.

J. Rusz, B. Benova, H. Ruzickova, M. Novotny, T. Tykalova, J. Hlavnicka, T. Uher, M. Vaneckova, M. Andelova, K. Novotna, L. Kadrnožkova, and D. Horakova. (2018). "Characteristics of motor speech phenotypes in multiple sclerosis," Multiple Sclerosis and Related Disorders, 19(1 January): 62-69.

J. Rusz, M. Novotny, J. Hlavnicka, T. Tykalova, and E. Ruzicka. (2017). High-accuracy voice-based classification between patients with Parkinson’s disease and other neurological diseases may be an easy task with inappropriate experimental design. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 25(8 August): 1319-1321.

J. Rusz, T. Tykalova, R. Krupicka, K. Zarubova, M. Novotny, R. Jech, Z. Szabo, and E. Ruzicka. (2017). "Comparative analysis of speech impairment and upper limb motor dysfunction in Parkinson’s disease," Journal of Neural Transmission, 124(4 April): 463-470.

J. Hlavnicka, R. Cmejla, T. Tykalova, K. sonka, E. Ruzicka, and J. Rusz (2017). "Automated analysis of connected speech reveals early biomarkers of Parkinson’s disease in patients with rapid eye movement sleep behaviour disorder," Scientific Reports, 7(February): 12.

T. Tykalova, J. Rusz, J. Klempir, R. Cmejla, and E. Ruzicka. (2017). "Distinct patterns of consonant articulation among Parkinson’s disease, progressive supranuclear palsy and multiple system atrophy," Brain and Language, 165(2 February): 1-9.

M. Novotny, J. Rusz, R. Cmejla, H. Ruzickova, J. Klempir, and E. Ruzicka. (2016). "Hypernasality associated with basal ganglia dysfunction: evidence from Parkinson’s disease and Huntington’s disease," PeerJ, 4(September): 2530.

J. Rusz, T. Tykalova, J. Klempir, R. Cmejla, and E. Ruzicka. (2016). "Effects of dopaminergic replacement therapy on motor speech disorders in Parkinson's disease: a longitudinal follow-up study on previously untreated patients," Journal of Neural Transmission, 123(4 April): 379-387.

J. Rusz, J. Hlavnicka, T. Tykalova, J. Buskova, O. Ulmanova, E. Ruzicka and K. sonka. (2016). "Quantitative assessment of motor speech abnormalities in idiopathic rapid eye movement sleep behaviour disorder," Sleep Medicine, 19(3 March): 141-147.

T. Tykalova, M. Pospisilova, R. Cmejla, J. Jerabek, P. Mares, J. Rusz. (2016). "Speech changes after coordinative training in patients with cerebellar ataxia: A pilot study," Neurological Sciences, 37(2 February): 293-296.

T. Tykalova, J. Rusz, R. Cmejla, J. Klempir, H. Ruzickova, J. Roth, and E. Ruzicka. (2015). "Effect of dopaminergic medication on speech dysfluency in Parkinson's disease: a longitudinal study," Journal of Neural Transmission, 122(8 August): 1135-1142.

J. Rusz, J. Hlavnicka, R. Cmejla, and E. Ruzicka. (2015). "Automatic evaluation of speech rhythm instability and acceleration in dysarthrias associated with basal ganglia dysfunction," Frontiers in Bioengineering and Biotechnology, 3(July):104

J. Rusz, C. Bonnet, J. Klempir, T. Tykalova, E. Baborova, M. Novotny, A. Rulseh, and E. Ruzicka. (2015). "Speech disorders reflect differing pathophysiology in Parkinson's disease, progressive supranuclear palsy and multiple system atrophy," Journal of Neurology, 262(4 April): 992-1001.

J. Rusz, J. Klempir, T. Tykalova, E. Baborova, R. Cmejla, E. Ruzicka, and J. Roth. (2014). "Characteristics and occurrence of speech impairment in Huntington's disease: possible influence of antipsychotic medication," Journal of Neural Transmission, 121(12 December): 655-664.

J. Rusz, C. Saft, U. Schlegel, R. Hoffman, S. Skodda. (2014). "Phonatory Dysfunction as a Preclinical Symptom of Huntington Disease," PLoS One, 9(11 November): e113412.

M. Novotny, J. Rusz, R. Cmejla, E. Ruzicka. (2014). Automatic evaluation of articulatory disorders in Parkinson's disease. IEEE/ACM Transactions on Audio, Speech, and Language Processing, 22(9 September): 1366-1378.

T. Tykalova, J. Rusz, R. Cmejla, H. Ruzickova, and E. Ruzicka. (2014). "Acoustic Investigation of Stress Patterns in Parkinson's Disease," Journal of Voice, 28(1 January): 129.e1-129.e8.

J. Rusz, R. Cmejla, T. Tykalova, H. Ruzickova, J. Klempir, Veronika Majerova, Jana Picmausova, Jan Roth, and E. Ruzicka. (2013). "Imprecise vowel articulation as a potential early marker of Parkinson’s disease: Effect of speaking task," Journal of the Acoustical Society of America, 134(3 October): 2171-2181.

J. Rusz, J. Klempir, E. Baborova, T. Tykalova, V. Majerova, R. Cmejla, E. Ruzicka, and J. Roth. (2013). "Objective Acoustic Quantification of Phonatory Dysfunction in Huntington's Disease," PLoS One, 8(6 June): e65881.

J. Rusz, R. Cmejla, H. Ruzickova , J. Klempir, V. Majerova, J. Picmausova, J. Roth, and E. Ruzicka. (2013). "Evaluation of speech impairment in early stages of Parkinson's disease: a prospective study with the role of pharmacotherapy," Journal of Neural Transmission, 120(2 February): 319-329.

J. Rusz, R. Cmejla, H. Ruzickova , J. Klempir, V. Majerova, J. Picmausova, J. Roth, and E. Ruzicka. (2011). "Acoustic assessment of voice and speech disorders in Parkinson’s disease through quick vocal test," Movement Disorders, 26(10): 1951-1952.

J. Rusz, R. Cmejla, H. Ruzickova , and E. Ruzicka. (2011). "Quantitative acoustic measurements for characterization of speech and voice disorders in early untreated Parkinson’s disease," Journal of the Acoustical Society of America, 129(1): 350-367.